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Department of Pathology
Research

Details of Research projects completed in 2015-16, 2016-17. 2017-18 and currently undertaken in Dept by Faculty, PG & UG - AFMRC/ ICMR/PG/Departmental

 

ICMR PROJECTS:

 

1

To evaluate clinic-pathologic pattern and Her2neu status in gastrointestinal malignancies.

Med Cdt C Gowtham Varma

2015

2

Comparison of normal saline & aqueous glycerin rehydration techniques for Papanicolaou staining of air dried smears.

Med Cdt Pranab Hinduja

2015

3

Correlation of Hormonal status of endometrial carcinoma with marker of tumor aggression

Med Cdt Som Subhra Goswami

2016

4

Is aerated soft drink and packaged juice consumption an independent risk factor to cause non-alcoholic fatty liver disease

Kunal Rajesh Kukreja

2017

5

Evaluation of platelet parameters in patients of ischemic heart disease and ischemic stroke

Krishna S Nair

2017

6

CD8 + lymphocyte Infiltration is an independent favorable prognostic indicator in basal-like breast cancer

Shantanu Khanna

2017

 

MUHS PROJECTS:

 


1

Hematological Changes in HIV Positive patients

Med Cdt Vasu Bansal

2017

2

To study the association of p53 expression with molecular subtypes of breast carcinoma

Med Cdt Sai Saran

2017

3

Measurement of platelet parameters in patients of ischemic heart disease

Med Cdt Nishant Raman

2017

4.

Association between Survivin Immunohistochemistry score & grading & staging in breast carcinomas

Med Cdt Saswat Satpathy

2018

 

COLLABORATIVE PROJECTS:

 


1

 Identification of Exosome derived biomarkers and Mutational analysis in High Grade Serous Ovarian Cancer (HGSOC) – a pilot project.

Gp Capt A Sen

2016

2

Clinical stratification of high-grade serous carcinoma using a panel of six biomarkers

Dr. Swapnil Kamble (NCCS), Gp Capt A Sen

2017

3

Pilot study for identification of new targets and biomarkers in haematological malignancies using integrated proteomics and metabolomics approaches

Dr. Srikanth Rapole (NCCS), Col Sanjeevan Sharma, Lt Col S Venkatesan

2017


AFMRC PROJECTS:

 


Distribution of Topo-isomerase II alpha (Top 2A) Gene Aberrations (Amplifications and Deletions) in relation to Her 2 Neu (C-erb B2) Oncogene status as determined by chromogenic in situ hybridization (CISH) in Breast Carcinoma Cases. 2014

Brig Reena Bharadwaj VSM

2014

Genetic Basis and Biological Mechanisms of Malignant Astrocytomas. 2014

Brig Reena Bharadwaj VSM

 2014

Genetic Analysis of the EGFR gene mutations and polymorphisms within exons 18, 19 and 21 with flanking intronic sequences in non small cell lung carcinoma. 2015

Brig Reena Bharadwaj VSM

2015

Rapid in situ hybridization (RISH) and immune-histochemistry: A pilot comparative study of two rapid diagnostic techniques for evaluation of establishing monoclonality in plasma cell dyscrasias.

Gp Capt Arijit Sen

2015

Assessment of podocyturia as an indicator of glomerular disease activity in cases of lupus nephritis

Col Rohit Tewari

2014

To study the role of SUPAR in objective assessment for biopsy for suspected cases of FSGS in patients of nephrotic syndrome.

Col Rohit Tewari

2015

Study of angiogenesis in invasive breast carcinoma by morphometry and immunohistochemistry

Col JK Bhatia

2016

A study somatic gene mutations in breast carcinoma

Col DK Raman

2016

Correlation between osteopontin expression and clinical profile in cases of Acute Myeloid Leukemia : 

Lt Col S Venkatesan

2016

A study of CYR61 (CNN1) and avb3 Integrin expression in Breast Carcinoma by RT-PCR and immunohistochemistry and its association with grade and stage of tumor

Col DK Raman

2016

Pilot Study on the BRAF (V600E) and RAS gene mutations in thyroid tumors. 

Surg Cdr Divya Shelly

2017

 

DEPARTMENTAL PROJECTS:

 

Clinicopathological correlation of FSGS and significance of serum suPAR levels in cases of FSGS who present with nephrotic syndrome in a tertiary care hospital.

Maj Sampath KS

2015

Comparison of various histopathological patterns amongst microsatellite instability high and microstable cases in colorectal carcinoma.

Maj K Vinu B

2015

Evaluation of E Cadherin and cyclin D1 in head and neck squamous cell carcinomas as markers of adhesion and clonal expansion

Maj Khushdeep Kaur

2015

Study of platelet function defects in CML.

Capt Zae Htet Min

2015

Clinico-pathological study of astrocytic tumours.

Dr Yashveer Sehrawat

2015

Study of tumour associated macrophages density in carcinoma breast.

Dr Imtiaz Ahmad

2015

Study of association of p53 expression with molecular subtypes of breast carcinoma.

Dr Naresh Gupta

2015

Correlation between microsatellite instability and ER, PR and Her2neu in carcinoma breast.

Dr Rajkumar M

2015

To subtype non-small cell lung cancer (NSCLC) as per new LASLC/ATS/ETS guidelines by using three immunohistochemistry markers p63, TTF-1 and Napsin A

Maj Shweta Singh Rathore

2016

A Case control study of Expression of Immunohistochemical markers ER, PR, Ki-67 and BCL-2 in Endometrial Hyperplasia/ Carcinoma with proliferative endometrium

Maj Kriti Agarwal

2016

Histopathological Study of Placentae in Low Birth Weight babies born at tertiary care hospital in Western India

Maj Manish Sharma

2016

Distribution of p16 in Head and Neck Squamous cell carcinoma

Capt Zamarak Noori

2016

Somatic Mutations Profile in Non-Hereditary Breast Carcinoma

Dr.Ritu Ranjan Kumar

2016

Rapid in Situ Hybridization (RISH) and Immunohistochemistry (IHC) : A Comparative Study of Two Rapid diagnostic techniques for evaluation of establishing monoclonality in Plasma cell dyscrasias

Dr.Gunveen Sachdeva

2016

Morphometric Analysis of Duodenal Mucosa in Coeliac Disease

Dr.Nabeel Azeez K

2016

Morphometric Analysis of Tumor Lymphangiogenesis in Head and Neck Squamous Cell Carcinomas

Maj Isha Sharma

2017

Study of CK5 and Estrogen receptor in breast usual ductal hyperplasia (UDH) and Atypical ductal hyperplasia (ADH)/ductal carcinoma

Maj Harish Kumar

2017

Study of Survivin biomarker in carcinoma colon

SLC Pratibha Chandra

 

Comparison of IgG4, C3d and C4d Immunohistochemistry with Direct Immunofluorescence in the diagnosis of Immuno-bullous disorders

Sqn Ldr RS Sikarwar

2017

Clinico-pathological and Immuno histochemical study (ER, PR, HER2/NEU) in Epithelial ovarian tumor

Maj Vaibhav Srivastava

2017

Comparison of WHO Traditional Grading and poorly differentiated clusters (PDC) Grading in Colorectal Adenocarcinoma

Maj MKS Parihar

2017

Assessment of Osteopontin expression in cases of acute myeloid leukemia

Lt Lida Faizi

2017

Morphometric and Immuno-histochemical study of angiogenesis in invasive ductal carcinoma breast

Dr.Tripta Chaudhary

2017

Study of prognostic biomarkers ER, PR, HER2 and  EGFR in epithelial ovarian carcinoma

Brig Reena Bharadwaj
VSM

2017

Morphometric study of head & neck squamous cell carcinoma (HNSCC)

Col JK Bhatia

2017

 

Details of papers read & poster presentations by Faculty in 2015, 2016 & 2017.

 

BRIG REENA BHARADWAJ VSM:

  • “Cytology of thyroid follicular lesions”-Maulana Azad Medical College, Delhi Chapter of Cytology-29 Jan 2015
  • Disability Pensions-At the Cross Roads-54th Armed Force Medical Research Conference, Pune-05 Feb 2015
  • “Cytology of the kidney-Through the looking glass.” At Indore in the MP Chapter of Pathology, 07 Feb 2015
  • Cytology of Renal Neoplasms-Guest Lecture at Karnataka Chapter of IAC on 29 Jan 2016.
  • ACOS conference New Delhi: Presented “Small biopsy interpretation of lung” from 08-10 Apr 2016.
  • Delivered Guest Lecture on Pathology of premalignant and malignant lesions of oral cavity during ENT conference at AFMC on 22 Apr 2016.
  • Delivered Guest lecture at Inamdar hospital in Oncopathology CME: Lung biopsy interpretation.
  • Delivered Guest Lecture on “Mucinous tumors of pancreas” at APCON 2016 at Jaipur.
  • Case presentations on “Role of cytology in soft tissue tumors” at CYTOCON 2016 at Nagpur.
  • Gave a talk in the Post conference Workshop on “Ancillary techniques in fluid cytology” at CYTOCN 2016 at Nagpur.
  • Conducted the Meet of the Pune chapter of the Indian association of Pathologists and Microbiologists at AFMC in Mar 2016.
  • Conducted a 4 day workshop on NABL accreditation procedures for lab personnel from 10-13 Dec 2016
  • Cytology of Renal Neoplasms-Guest Lecture at Karnataka Chapter of IAC on 29 Jan 2016.Delivered Guest Lecture on “Pathology of pre-malignant and malignant lesions of oral cavity”, during ENT conference at AFMC, Pune on 20Apr 2017.
  • Conducted a CPC at Command Hospital Central Command Lucknow on a case of Sclerosing Mediastinitis in 09Jul 2017(During Annual Leave).
  • Delivered Guest lecture at MAPCON“ The Bethseda system of reporting Thyroid Neoplasms”, in Sholapur on 08-10Sep 2017 and did Case presentations on “Slide Seminar” along with chairing of two sessions.
  • Conducted a Pre Conference workshop on “Cytology of Lymphoid Lesions-Neoplastic and Non Neoplastic“ in CYTOCON at Shillong on 10Nov 2017.
  • Presented a paper on “Role of Cytology in detection of Infections in Immunosuppressed individuals”, in 52 nd World Congress ICMM on 23 Nov at New Delhi
  • Delivered Guest lecture on “Small Biopsy Interpretation in Lung-A Paradigm shift ”, and presented cases in “Endocrine Symposium” at APCON 2017 on 08-09 Dec at Bhopal.

GP CAPT ARIJIT SEN

  • Poster- "Cytology in an extremely rare case of non contiguous multifocal synchronous extranodal Non Hodgkin's Lymphoma intermediate between DLBCL and Burkitt's - a case report" Cytocon 2017.
  • Case presentation in Lymphoma Preconference CME- Cytocon 2017.

 

COL JK BHATIA

  • Nikhil Deshpande, Col J K Bhatia, Col Kavita Sahai, Col Ajoy Menon, Brig VS Nijhawan. Matters of the heart: Three unusual cases of heart tumours. Poster presented at MAPCON 2015.
  • Oral Presentation in Scientific Session: Medical Cover during Military Operations in 42nd ICMM World Congress on Military Medicine:  19th to 24th November 2017 for the paper titled ‘Pattern of Fatal Injuries in Counter Terrorist Operations: An Innovative Analysis through Embalming Services’
  • Presented cases for PG quiz in 38th Annual chapter conference of IAPM - MAPCON 2017 at Solapur

GP CAPT PRATEEK KINRA

  • Laboratory investigations in a case of comatose patient: CME on Emergencies, 6 Air Force Hospital, Coimbatore: 23-24 Apr 2015.
  • Study of immunological parameters in simulated microgravity. ASMA, Florida USA: 10-15 May 15.
  • Moderated a panel discussion on oncopathology. Army Hospital R&R Delhi. 18-19 Aug 15
  • Drugs in aviation. ISAM Bangalore. 29 Aug 15.
  • Practices and procedures for laboratory accreditation in service hospitals. CME on NABH Assessors Workshop. 4-5 Sep 15.
  • Timing of injury. Aviation Accident Investigation CME. IAM Bangalore. 06 Jun 16.
  • Inflammatory Disorders; Dermatopathology CME, CHAF, Bangalore. 21 Aug 16.
  • Conducted and presented CME on Pancreatic cysts during APCON 2016 (1-4 Dec 16), BM Birla Auditorium. Jaipur.
  • Attended International Pathology CME – Grand Sheraton
  • Poster presentation- 42nd ICMM, New Delhi ‘Topical gene therapy (sonic hedgehog gene) for accelerated wound healing in battle trauma care: a meta-analysis’
  • Slide seminar (Pancreas and GIT endocrine pathology)- 66th APCON, Bhopal ‘Insulinoma, goblet cell carcinoid, mixed adenocarcinoma neuroendocrine carcinoma’

COL DK RAMAN

  • Poster presentation- APCON 2016-Lymphomatoid Granulomatosis - Unusual presentation - DK Raman, A Bhatnagar, A Sood, Reena Bharadwaj
  • Poster presentation- APCON 2016Evaluation of Endocrine pathology Working Groups Novel criteria for diagnosing 'Non-invasive Follicular Thyroid neoplasm with papillary like nuclear features' Naresh Gupta, DK Raman, Divya Shelly, Manoj MG, Reena Bharadwaj. 
  • 2017 – MAPCON: Presented a slide seminar on thyroid Cytology during MAPCON 2017 (Annual conference of Maharastra Chapter of IAPM).
  • Moderated a slide seminar on Endocrine Pathology  during APCON 2017 (Annual National Conference of  IAPM)
  • Two poster presentations and one oral papers presented by PG students under guidance in APCON and MAPCON 2017

LT COL S VENKATESAN

  • Evaluation of bone marrow microvessel density in patients with aplastic anaemia and its role in predicting outcome to therapy’ in Haematocon 2015, 56th  annual conference of Indian Society of Hematology and Blood Transfusion  (Nov 2015)
  • Delivered 03 talks and conducted 01 slide seminar in the Zonal CME for  Post Graduates, Dr NTR University Of Health Sciences, Vjaywada organized by G.S.L Medical College, Rajahmundry on 22nd Nov 2015 (talk on bone marrow biopsy, HSCT, Classification on AML)
  • 57th   Annual Conference of the Indian Society of Hematology and Blood Transfusion (Hematocon 2016, 10-13 Nov 2016, Jaipur) and presented poster on “Unusual Presentations of Plasma cell neoplasms- Case Series from a Tertiary Care Centre”.
  • Chaired a session in “Benign Haematology” at Hematocon 2016, 10-13 Nov 2016, Jaipur.
  • MAPCON 2016, at Dr DY Patil Medical College, Navi Mumbai, Sep 2016 and presented a case of “Cold Agglutin Disease” in PG QUIZ.
  • Best of EHA-2016, 23rd-24th July 2016,Mumbai.
  • Delivered a talk on “AN APPROACH TO COAGULOPATHY IN THE CRITICALLY ILL” during the MEDUCATION 2016 (CME ON HEMATOLOGY) on 6 th April 2016 in PDVVPF’s Medical College Campus, Ahmednagar.
  • 2nd ISHBT EHA Tutorial, Mumbai, 29th to 31st January,2016.
  • CME in Hematopathology, delivered talk on ‘approach to bleeding disorder’ on 09 Jul 2017 at AIIMS JODHPUR.
  • Conducted a Workshop on Hemogram for UGs in Illuminati on 08 Sep 17.
  • Lecture on “approach to thrombocytopenia” on hematology CME on 25 Nov 2017 held at CH(SC).
  • Presentation on Waldenstorm’s Macroglobulinemia in station clinical meet, Dec 2017.
  • Attended Annual conference of association of Indian Hematology and Blood transfusion society  “Hematocon 2017’, Nov 2017 and presented poster on “. Clinico- pathological profile of Waldenstorm’s Macroglobulinemia: A tertiary care center experience of Six cases”

SURG CDR DIVYA SHELLY

  • Poster in Hematocon 2015: Biclonal chronic lymphocytic leukemia-a case report.

LT COL PARESH SINGHAL

  • Klinefelter Syndrome: Clinical and cytogenetics study from a tertiary care center- Indian Society of Human Genetics (2015)
  • Cytogenetics abnormalities in 2000 couples with recurrent pregnancy loss- APCON (2016)